top of page

Technology
About
Careers

HolisticA

Root-Cause Medicine

Chronic Fatigue

Watch 5-Minute Video:

How to Get Back to Predictable, Reliable, Daily Energy

Watch 37-Minute Video from our YouTube Channel:

Deep Dive Medical Video on Chronic Fatigue:

Quiz Revealing Source(s) of Your Chronic Fatigue

Section 1 - Mitochondrial Breakdown (Energy Production)

Low Stamina during normal daily activities? *

Never

Rarely

Sometimes

Often

Always

Muscles fatique quickly during mild exertion? *

Never

Rarely

Sometimes

Often

Always

Feeling "wired but tired" after physical activity? *

Never

Rarely

Sometimes

Often

Always

Section 2 - HPA Axis Dysregulation (Stress Response)

Difficulty bouncing back from stress? *

Never

Rarely

Sometimes

Often

Always

Energy crashes between 2-5 PM? *

Never

Rarely

Sometimes

Often

Always

Feeling overwhelmed by small tasks? *

Never

Rarely

Sometimes

Often

Always

Section 3 - Dysbiosis & Leaky Gut

Bloating, gas or digestive discomfort? *

Never

Rarely

Sometimes

Often

Always

Fatigue after meals? *

Never

Rarely

Sometimes

Often

Always

Food sensitivities or reactions? *

Never

Rarely

Sometimes

Often

Always

Section 4 - Nutrient Deficiency

Cravings for sugar, salt, or stimulants? *

Never

Rarely

Sometimes

Often

Always

Brittle nails, hair thinning, or dry skin? *

Never

Rarely

Sometimes

Often

Always

Fatigue improves temporarily after eating? *

Never

Rarely

Sometimes

Often

Always

Section 5 - Toxic Burden

Sensitivity to chemicals, fragrances, or smoke? *

Never

Rarely

Sometimes

Often

Always

Headaches or brain fog in certain environments? *

Never

Rarely

Sometimes

Often

Always

Fatigue that worsens after exposure to pollutants? *

Never

Rarely

Sometimes

Often

Always

Section 6 - Infection & Immune Challenges

Frequent colds or slow recovery from illness? *

Never

Rarely

Sometimes

Often

Always

Swollen lymph nodes or sore throat without infection? *

Never

Rarely

Sometimes

Often

Always

Fatigue that worsens after physical or mental stress? *

Never

Rarely

Sometimes

Often

Always

Section 7 - Sleep & Circadian Rhythm Disruption

Trouble falling or staying asleep? *

Never

Rarely

Sometimes

Often

Always

Waking unrefreshed even after a full night's sleep? *

Never

Rarely

Sometimes

Often

Always

Energy peaks late at night? *

Never

Rarely

Sometimes

Often

Always

Section 8 - Methylation Imbalance

Mood swings or irritability? *

Never

Rarely

Sometimes

Often

Always

Difficulty concentrating or staying motivated? *

Never

Rarely

Sometimes

Often

Always

Fatigue that improves with B-vitamin supplements? *

Never

Rarely

Sometimes

Often

Always

Section 9 - Low-Grade Inflammation

Joint stiffness or body aches without injury? *

Never

Rarely

Sometimes

Often

Always

Puffy face or hands? *

Never

Rarely

Sometimes

Often

Always

Fatigue that worsens after inflammatory foods? *

Never

Rarely

Sometimes

Often

Always

Section 10 - Neurotransmitter Imbalance

Low mood or lack of pleasure? *

Never

Rarely

Sometimes

Often

Always

Racing thoughts or anxiety? *

Never

Rarely

Sometimes

Often

Always

Cravings for caffeine or stimulants to function? *

Never

Rarely

Sometimes

Often

Always

Section 11 - Neuroinflammation

Persistent brain fog? *

Never

Rarely

Sometimes

Often

Always

Light or soud sensitivity? *

Never

Rarely

Sometimes

Often

Always

Head pressure or congitive fatigue? *

Never

Rarely

Sometimes

Often

Always

Section 12 - Autonomic Nervous System Imbalance (Dysautonomia)

Dizziness when standing up? *

Never

Rarely

Sometimes

Often

Always

Heart palpitations unrelated to exertion? *

Never

Rarely

Sometimes

Often

Always

Temperature intolerance (hot or cold)? *

Never

Rarely

Sometimes

Often

Always

Section 13 - Oral Infection / Dental Contributors

Chronic bad breath or metallic taste? *

Never

Rarely

Sometimes

Often

Always

Jaw tension or pain? *

Never

Rarely

Sometimes

Often

Always

History of dental infections or root canals? *

Never

Rarely

Sometimes

Often

Always

1. Mitochondrial Breakdown:

2. HPA Axis Dysregulation:

3. Dysbiosis & Leaky Gut:

4. Nutrient Deficiency:

5. Toxic Burden:

6. Infection & Immune Challenges:

7. Sleep & Circadian Rhythm Disruption:

8. Methylation Imbalance:

9. Low-Grade Inflammation:

10. Neurotransmitter Imbalance:

11. Neuroinflammation:

12. Autonomic Nervous System Imbalance:

13. Oral Infection / Dental Contributors:

Myth Busting

Myth 1: Chronic fatigue is just being tired
It’s a multi‑system dysfunction, not ordinary tiredness.

Myth 2: It's all in your head
Fatigue often reflects measurable biological imbalances, not imagination.

Myth 3: If you sleep more, it will go away
Sleep helps, but circadian disruption, mitochondrial issues, or inflammation can persist regardless.

Myth 4: Blood tests are normal, so nothing is wrong
Standard labs often miss subtle dysfunctions like nutrient insufficiency or HPA axis dysregulation.

Myth 5: Chronic fatigue is caused by laziness
People with chronic fatigue often push themselves far beyond their physiological capacity.

Myth 6: Only depression causes chronic fatigue
Mood changes can coexist, but fatigue can stem from immune, gut, mitochondrial, or neurochemical issues.

Myth 7: If you exercise more, you’ll get your energy back
Overexertion can worsen symptoms when mitochondria, inflammation, or autonomic balance are impaired.

Myth 8: Chronic fatigue is the same for everyone
Different root causes create different fatigue patterns—immune‑driven, gut‑driven, hormonal, neurological, etc.

Myth 9: Fatigue is always caused by stress
Stress matters, but so do toxins, infections, nutrient gaps, and gut dysfunction.

Myth 10: If you just eat healthier, the fatigue will disappear
Nutrition helps, but deeper issues like methylation imbalance or neuroinflammation may persist.

Myth 11: Chronic fatigue is rare
It’s extremely common—many people experience persistent fatigue without a clear diagnosis.

Myth 12: You can fix chronic fatigue with supplements alone
Supplements may support physiology, but root causes often require broader lifestyle and environmental changes.

Myth 13: Fatigue means you’re getting older
Age can influence energy, but persistent fatigue is not an inevitable part of aging.

Myth 14: If you don’t look sick, you’re fine
Many root causes—like dysbiosis, inflammation, or neurotransmitter imbalance—are invisible externally.

Myth 15: Chronic fatigue is caused by one single issue
It’s usually multi‑factorial, involving several systems simultaneously.

Myth 16: You can power through fatigue if you try hard enough
Pushing through can worsen mitochondrial strain and autonomic imbalance.

Myth 17: Fatigue is always caused by low iron or anemiaNutrient deficiency is one cause, but far from the only one.

Myth 18: If you’re fatigued, you must have a thyroid problem
Thyroid issues can contribute, but many people with fatigue have normal thyroid function.

Myth 19: Chronic fatigue is permanent
Many people improve when underlying imbalances are identified and addressed.

Myth 20: Oral health has nothing to do with fatigue
Oral infections can influence inflammation, immune load, and systemic energy levels.

5 Archetypical Profiles of Chronic Fatigue

The Wired Sleeper

Description:

HPA axis dysregulation + cortisol collapse.
Stuck in a loop of core exhaustion and insomnia.
Feels “tired and wired” – unable to rest and constantly fatigued

Traits:

Difficulty falling asleep despite exhaustion
Morning fatigue, afternoon crashes, nighttime alertness
Often misdiagnosed as anxiety or depression

The Foggy Thinker

Description:

Mitochondrial collapse + neuroinflammation
Struggles with memory, focus, and motivation
Feels like their brain is wrapped in cotton

Traits:

Brain fog, poor recall, slow processing
Fatigue worsens with exertion or stress
Often dismissed as "burnout" or "getting older"

The Detox Blocker

Description:

Mycotoxin overload + sluggish detox pathways
Sensitive to smells, chemicals, and environments
Feels like their body is holding onto invisible toxins

Traits:

Fatigue, headaches, chemical sensitivity
Poor recovery and emotional flatness
Often told "it's all in your head"

The Gut-Derailed Reactor

Description:

Dysbiosis + malabsorption
Experiences bloating, food sensitivities, and post-meal crashes
Feels like their gut is sabotaging their energy

Traits:

Fatigue after meals or infections
Brain fog, mood swings, and digestive discomfort
Often misdiagnosed as IBS or psychosomatic

The Nutrient Starved Achiever

Description:

Micronutrient depletion + poor absorption
Eats well, supplements often, but still feels depleted
Feels like their cells are starving despite effort

Traits:

Fatigue, poor focus, muscle cramps
Symptoms worsen with stress or fasting
Often told "labs are normal"

Nutrient-Starved Achiever_2.png

Disclaimer: The information on this website is provided for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. These statements have not been evaluated by the Food and Drug Administration. Our services and the information provided are not intended to diagnose, treat, cure, or prevent any disease. References to specific functional medicine markers or supportive therapies represent a clinical methodology and are not a guarantee of specific outcomes. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before beginning any new health or therapy program.

bottom of page